Autism subtyping of pre-school aged children

This project has the following objectives:

• To determine the clinical characteristics that predict outcomes in pre-school aged children on the autism spectrum
• To evaluate the clinical, behavioural, family and psychosocial modifiers and predictors of outcomes
• To compare the developmental trajectory using clinical (phenotypes) and neurocognitive markers (endophenotypes) in relation to treatment outcome to determine homogeneous subgroups
• To incorporate the clinical, behavioural and neurocognitive profile together with the genetic/molecular signature available from project 1.2 to yield biological subtypes.